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It was a perfect Week 1 for the Pac-12. The conference’s 12 teams all won their games and enter Week 2 of the college football season with a 13-0 record after USC also won in Week 0. Seven of the 12 teams scored at least 40 points in the most dominating weekend for a single conference to open the 2023 college football season. Seven of the 11 games played by Pac-12 teams have a one-score margin in the latest Week 2 college football odds.
It will be much more challenging for the conference to have another undefeated week, but the Week 2 college football schedule should show positive results for the conference. No. 6 USC (-29.5) plays Stanford and UCLA (-13) plays San Diego State as large favorites. Arizona (+10) is the conference’s largest underdog playing at Mississippi State in Week 2 of the college football season. Before locking in any college football picks on those games or others, be sure to see the latest college football predictions from SportsLine’s proven model.
The SportsLine Projection Model simulates every FBS college football game 10,000 times. The proprietary computer model is off to a fast 4-2 start on all-top rated college football picks this season. Since its inception, it has generated a stunning profit of more than $2,500 for $100 players on its top-rated college football picks against the spread. Anyone who has followed it has seen huge returns.
Now, it has turned its attention to the latest college football odds for Week 2 and locked in picks for every FBS matchup. Head here to see every pick.
Top college football predictions for Week 2
One of the college football picks the model is recommending for Saturday: Cincinnati (+8) easily covers against Pittsburgh on Saturday in a 6:30 p.m. ET kickoff at Acrisure Stadium. Quarterback Emory Jones showed off his potential when he completed 19-of-23 passes for 345 yards and five touchdowns in Cincinnati’s opener after failing to throw for 300 yards in any of his eight games at Arizona State last year. He also added two rushing scores in the 66-13 win over Eastern Kentucky.
Jones and receiver Xzavier Henderson were teammates for one year at Florida before the two eventually teamed up in Cincinnati. It didn’t take long for their connection to shine as Henderson had seven receptions for 149 yards and a touchdown in Week 1. Henderson led Florida with 38 receptions before transferring to Cincinnati and he and Jones can form a dynamic duo for the Bearcats. Jones is projected to throw for 231 yards in the model’s latest simulations, which is one reason why the Bearcats are covering the spread 70% of the time.
Another prediction: No. 4 Alabama cruises to a blowout win as a 7-point home favorite against No. 11 Texas on Saturday at 7 p.m. ET. Jalen Milroe proved ready to take over for Bryce Young at quarterback with five total touchdowns in a 56-7 win over Middle Tennessee last week. The sophomore completed 13-of-18 passes for 194 yards and three touchdowns while adding 38 rushing yards and two scores. Texas is certainly a much tougher opponent than Middle Tennessee, but Milroe passed his first test.
The Crimson Tide are coming off an 11-2 season and missing the College Football Playoff, their worst year since 2019, and you can be sure Nick Saban is reminding this year’s team of last season’s failures. Alabama defeated Texas, 20-19, in Austin last year but this will be the first time the two schools meet in Tuscaloosa since 1902. Alabama is 13-5-1 at home against the spread over its last three seasons. Texas is 2-5 in its last seven games against SEC opponents, including 0-4 in its last four regular-season matchups, which is one reason why Alabama is covering the spread in well over 60% of simulations. See which other teams the model likes here.
How to make college football picks for Week 2
The model has also made the call on who wins and covers in every other FBS matchup in Week 2, and it’s calling for several underdogs to win outright. You can only get every pick for every game at SportsLine.
So what college football picks can you make with confidence, and which underdogs win outright? Check out the latest college football odds below, then visit SportsLine to see which teams win and cover the spread, all from a proven computer model that has returned more than $2,500 in profit since its inception, and find out.
College football odds for Week 2 top games
See full Week 2 college football picks, odds, predictions here
Friday, Sept. 8
Saturday, Sept. 9
Vanderbilt at Wake Forest (-11.5, 58.5)
Ball State at Georgia (-42, 53)
Notre Dame at NC State (+7.5, 50)
Nebraska at Colorado (-3, 58.5)
Texas A&M at Miami (FL) (+4, 49)
Iowa at Iowa State (+4, 36.5)
Cincinnati at Pittsburgh (-8, 48.5)
Texas at Alabama (-7, 56.5)
Oregon at Texas Tech (+6.5, 67)
Wisconsin at Washington State (+4, 54.5)
Oklahoma State at Arizona State (+3.5, 53)
